When you're choosing a data acquisition recorder, the fundamental decision is whether you need a fixed set of channels at a low entry price or a configurable, multifunction system that can handle a wider variety of measurements. Two used units capture this trade-off clearly: the Axon Instruments DigiData 1322A, a 16-bit digitizer at $249.99, and the Keithley DAQ6510 Data Acquisition DMM6500 Multimeter System at $1,600.00. The $1,350 gap between them isn't just about features; it's about two different philosophies of laboratory instrumentation.
Quick Verdict
If you need a ready-to-run digitizer with a broad channel set and don't want to overspend, the Axon DigiData 1322A is the pragmatic choice. It gives you a complete, immediately usable I/O layout for a modest investment. If you're investing in a more modular platform that can grow with your lab, the Keithley DAQ6510 is the more substantial option.
Comparison Table
| Feature | Axon DigiData 1322A | Keithley DAQ6510 |
|---|---|---|
| Price | $249.99 | $1,600.00 |
| Brand | Axon Instruments | Keithley |
| Condition | Used | Used |
| Type | Data acquisition system / digitizer | Data acquisition / multimeter system |
| Resolution | 16-bit | - |
| Analog input channels | 16 | - |
| Analog output channels | 2 | - |
| Digital I/O | 16 in / 16 out | - |
| Interface | SCSI | - |
| Slots | - | 2 |
| Origin | Made in USA | China |
Where Each Product Wins
Axon DigiData 1322A wins on price and channel count. For a fraction of the cost of the Keithley, you get a broad set of analog and digital I/O, making it the obvious choice for multi-channel acquisition on a budget. Its rack-mount design suits a permanent lab installation.
Keithley DAQ6510 wins on integration and modularity. It's designed as a more adaptable platform, with a modular architecture that points to a tailorable setup. The higher price buys a more versatile instrument that can take on a wider range of measurement duties.
Product Notes
Axon Instruments DigiData 1322A 16-Bit Data Acquisition System
The Axon DigiData 1322A is a rack-mount digitizer built for scientific research, with 16-bit resolution, 16 analog input channels, 2 analog output channels, and 16 digital inputs plus 16 digital outputs. That's a generous fixed set of signal paths for a modest outlay. The used unit powers on with POWER and READY indicators illuminated, and its SCSI interface and Made-in-USA construction point to a lab-grade design. It's the right pick when you need multi-channel acquisition without stretching your budget, or if you're working in electrophysiology where the 16-bit resolution and analog channel count are directly useful. The main limitation is the SCSI computer connection, which can be awkward to pair with a modern PC without an adapter. It's a dedicated digitizer with a fixed set of inputs, so plan your recording setup around those 16 channels and don't expect to swap modules later.
Keithley DAQ6510 Data Acquisition DMM6500 Multimeter System
The Keithley DAQ6510 takes a different approach. Instead of a fixed channel layout, it combines data acquisition with a multimeter system in its title, and its 2-slot configuration suggests a modular platform you can tailor to your needs. The used unit is built in China and is the costlier option here, but the high price reflects a more ambitious architecture. Go with this when you want a single instrument that handles both data recording and multimeter measurements, and when your budget allows a more adaptable station. The limitation is the hefty price; for smaller labs or one-off projects, the investment is hard to justify compared to the Axon's low cost. If your tasks really demand a multifunction system, the DAQ6510 offers a different set of capabilities that the fixed Axon cannot match.
Final Choice by Use Case
For immediate, multi-channel recording at a modest investment, the Axon DigiData 1322A is the answer. For a modular, integrated measurement platform that can take on a wider range of tasks, the Keithley DAQ6510 is the one to build around. Choose the Axon when you know exactly what you need today; choose the Keithley when you expect tomorrow's applications to be broader.

