When you are comparing data acquisition recorders, the first fork is clear: do you need a recorder that is built around low-noise signal capture, or do you need a unit that also behaves like a general-purpose measurement system? The Axon Digidata 1550A with HumSilencer and the Keithley DAQ6510 with DMM6500 multimeter system sit at different ends of that trade-off.
Quick verdict
The Axon Digidata 1550A with HumSilencer is the dedicated low-noise recorder. The Keithley DAQ6510 is the more versatile instrument, pairing data acquisition with a DMM6500 multimeter system. Both units are listed as used, so the decision comes down to whether low-noise specialization or all-around measurement flexibility matters more to your lab.
Comparison at a glance
| Axon Digidata 1550A | Keithley DAQ6510 | |
|---|---|---|
| Listed price | USD 4,999.99 | USD 1,600.00 |
| Focus | Low-noise data acquisition plus HumSilencer | Data acquisition with DMM6500 multimeter system |
| Configuration | Low-noise acquisition bundle | 2-slot data acquisition system |
| Country of origin | United States | China |
| Condition | Used | Used |
Where each product wins
The Axon Digidata 1550A wins when signal integrity is the main concern. The title centers on low-noise acquisition and HumSilencer, so the entire package points to clean recording in environments where hum can interfere. If that is your daily work, the added investment is easier to justify.
The Keithley DAQ6510 wins when you need broader measurement capability. Its title pairs DAQ6510 data acquisition with the DMM6500 multimeter system, so it covers measurement duties beyond simple logging. For a teaching bench, a general lab station, or a project with diverse signal types, it covers more ground.
Product notes
Axon Digidata 1550A Low-Noise Data Acquisition System plus HumSilencer
The Digidata 1550A makes sense when your recordings are small enough that interference matters. The product title puts low-noise performance first and bundles HumSilencer, so the unit is clearly oriented toward clean data capture. That focus is also the limitation: if your tasks are mostly general-purpose logging or multimeter-style checks, the Axon's specialized design may be more than you need. Its country of origin is the United States, which is useful to know for purchasing requirements. If the majority of your measurements are small analog signals, the low-noise direction is exactly what the title promises. The bundle keeps HumSilencer in the same package, so there is no separate hum-reduction accessory to match.
Keithley DAQ6510 Data Acquisition DMM6500 Multimeter System
The Keithley DAQ6510 appeals when you want one box that can handle a range of measurement jobs. The title combines DAQ6510 data acquisition with the DMM6500 multimeter system, and the 2-slot design is a useful specification. The main trade-off is focus: the Axon Digidata 1550A's low-noise and HumSilencer package is more purpose-built for extremely quiet signal capture, while the Keithley's identity is broader. That broader identity is an advantage when your measurements vary, but it means the system is not pitched at extremely quiet recording in the way the Axon is. For labs that want one flexible data acquisition recorder, the Keithley is the easier fit.
Final choice by use case
If the job is extremely low-level signal capture and you want the HumSilencer bundle included, choose the Axon Digidata 1550A at USD 4,999.99. If you want a 2-slot data acquisition recorder with DMM6500 multimeter functions and a USD 1,600.00 listed price, choose the Keithley DAQ6510.

