Choosing between data acquisition recorders often comes down to workflow: do you need a multi-channel lab digitizer for biological signals, or a compact USB logger for temperature and low-voltage tracking? The Axon Instruments DigiData 1322A and Pico Technology USB TC-08 answer that question differently, and their $249.99 to $325 price spread reflects more than just condition.
Quick Verdict
Pick the Axon DigiData 1322A if you need 16 analog input channels, 16-bit resolution, and built-in digital I/O for patch-clamp or other scientific research setups. Pick the Pico TC-08 if you want a newer open-box USB unit with thermocouple input, a factory calibration certificate, and PicoLog software for temperature and low-voltage tracking.
At a Glance
| Feature | Axon DigiData 1322A | Pico TC-08 |
|---|---|---|
| Price | $249.99 | $325.00 |
| Condition | Used | New - Open Box |
| Interface | SCSI | USB |
| Channel Focus | 16 analog inputs + 16 digital I/O | 8 thermocouple channels |
| Resolution | 16-bit | High resolution for temperature and voltage |
| Included Cables/Software | Not specified | USB cable, software disc, installation guide |
Where Each Product Wins
The DigiData 1322A wins for channel count and research breadth. Its 16 analog input channels, 2 analog output channels, and 16 digital input/output lines make it a strong fit for labs that need to capture many signals simultaneously. The 16-bit resolution and rack-mount form factor point toward a permanent benchtop setup. The unit powers on with POWER and READY indicators lit, as confirmed in the listing description.
The Pico TC-08 wins for convenience and thermocouple-focused logging. It connects over USB, so you can pair it with a laptop quickly. It measures temperature and voltage up to ±70 mV, and the kit includes the logger, USB cable, software disc, installation guide, and factory calibration certificate envelope. Being new open-box means the hardware was inventoried and kept clean, but the outer box was opened.
Product Notes
Axon Instruments DigiData 1322A 16-Bit Data Acquisition System SCSI USA
If your research involves electrophysiology, patch-clamp, or biological signal acquisition, the DigiData 1322A is built specifically for that work. It gives you 16 analog input channels, 2 analog output channels, and 16 lines each of digital input and output. The 16-bit resolution and SCSI computer interface point to a dedicated lab instrument rather than a portable logger. It is a used unit, so you are buying a known condition rather than a factory-sealed product. The description confirms it powers on with the POWER and READY indicators illuminated, and the rack-mount design suits a stationary setup. The main limitation is the SCSI interface, which may require an adapter or older computer depending on your lab. If you need a multi-channel digitizer and can work with SCSI, the $249.99 price makes this an attractive option.
Pico Technology USB TC-08 Thermocouple Data Logger (Model PP222) - New/Open Box
If your priority is straightforward temperature logging over USB, the Pico TC-08 is the more convenient choice. It is an 8-channel thermocouple data logger that also measures low voltages up to ±70 mV, making it useful for temperature tracking and small-signal voltage monitoring. The complete kit includes the logger unit, USB cable, software disc, installation guide, and factory calibration certificate envelope. PicoLog software handles the recording, so you can start capturing data without assembling a custom rig. The condition is new open box, meaning the outer box was opened for inspection but the contents are clean and carefully maintained. The limitation is that its channel count is lower than the DigiData's 16 analog inputs, and its voltage range is confined to ±70 mV. At $325, you are paying for USB simplicity, thermocouple readiness, and a calibration certificate.
Final Choice by Use Case
For a multi-channel electrophysiology or bio-signal research setup, the Axon DigiData 1322A is the stronger pick because of its 16 analog inputs, digital I/O, and 16-bit resolution.
For portable temperature logging with a thermocouple probe and quick USB connection, the Pico TC-08 is the better fit, especially with its included calibration certificate and PicoLog software.
If your budget is tight and your lab already uses SCSI, the DigiData's lower price gives you more channels per dollar. If you want a newer unit that is ready to run from a USB port, the Pico TC-08 justifies its higher price with convenience and thermocouple support.

